Acquired haemophilia is not inherited, and cannot be passed on in the family. It may develop suddenly when a person's immune system starts to interfere with his/her own clotting factors by mistake. This reduction in the amount of clotting factor prevents the blood from clotting naturally, so bleeding continues.
Factor VII (FVII) deficiency is a rare inherited bleeding disorder affecting both males and females. The frequency and severity of bleeding episodes varies from person to person. Some people with FVII deficiency experience spontaneous, uncontrolled bleeding while in others the condition is less severe. Surgical bleeding is a major concern for people with FVII deficiency.
Glanzmann's thrombasthenia (GT) is a rare inherited bleeding disorder affecting platelets. Platelets are cells in the blood which stick to each other in a clump at the site of bleeding. This helps to stop the bleeding and forms a platform for the rest of the clotting process to take place.
GT is caused by a deficiency in or dysfunction of the GPIIb-IIIa protein on platelets. This protein is important to make platelets 'stick' to each other at the site of bleeding. In people with GT, serious bleeds can occur spontaneously and from trivial injuries, such as losing baby teeth in childhood and in relation to surgery.